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Complementary and Alternative Medicine

PC-SPES Lowers Prostate Specific Antigen Levels but Induces Estrogenic Effects

Published in Cancer Weekly, November 14th, 2000

In humans, in an animal model, and in in vitro analysis, the herbal therapeutic PC-SPES diminishes evidence of prostate cancer, but at the cost of generating estrogen-type side effects.

PC-SPES is a combination of eight Chinese herbs sold as a nutritional supplement in capsule form.

An analysis of PC-SPES was carried out in New York at the Columbia Presbyterian Medical Center using mice and cultured prostrate tumor cells, as well as 69 human study participants.

In vitro analysis showed that the three cell lines responded to PC-SPES. "All of the cultured prostate cancer cell lines had a significant dose-dependent induction of...

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