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Head and Neck Cancer

Targeted Chemoradiation Therapy Effective for Advanced Disease Control

Published in Cancer Weekly, November 28th, 2000

A combination of radiation therapy and chemotherapy targeted directly to tumors can provide effective control for patients with advanced head and neck cancer, researchers in the United States report.

K.T. Robbins and colleagues at the University of Tennessee conducted a study "to determine the survival results, patterns of relapse, and organ preservation effects of a targeted chemoradiation protocol for patients with advanced (stage III-IV) carcinoma of the head and neck."

The course of treatment evaluated by Robbins et al. consisted of four weeks of intra-arterial, 150 mg/m2 cisplatin infusions delivered rapidly to the tumor, coupled...

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