Ovarian Cancer

Fibroblast Growth Factor and Its Receptors Common to Ovarian Tumors

Published in Cancer Weekly, January 16th, 2001

Fibroblast growth factor (FGF)-8, a growth factor known for its mitogenic properties, could be a marker for ovarian cancer due to its relatively common expression on ovarian cancer cells, according to a new study.

Researchers in Finland at the University of Turku have identified several FGF-8 isoforms on human ovarian tumors and cells grown in culture. In addition, they have found that several FGF receptors are commonly found on a number of types of normal ovarian cells as well as cancerous cells.

E. Valve and associates at the MediCity Research Lab in Turku examined five normal human ovaries and 51 ovarian tumors for differences in FGF-8 isoform...

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Source: Cancer Weekly (2001-01-16)

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