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Breast Cancer

Tamoxifen Analogue Toremifene Not as Toxic to Liver

Published in Cancer Weekly, January 23rd, 2001

The new drug toremifene, a drug with anti-estrogen activity similar to tamoxifen, does not cause as many liver-related disorders in breast cancer patients, according to new research.

Fatty liver was observed in as many as 30% of women with breast cancers who were taking tamoxifen, N. Hamada et al. stated recently in the International Journal of Oncology. Hamada's research team works at Kochi Medical School in Japan.

"It is urgent to elucidate the frequency and the degree of fatty liver induced by toremifene, an analogue of tamoxifen, which is also used in breast cancer," the group commented.

Hamada's study enlisted 52...

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