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DNA Transfer

Protein Opens Door for Transfer from Bacteria to Plants

Published in Cancer Weekly, January 23rd, 2001

In the only known example of the transfer of genetic material between the plant and animal kingdoms, a tumor-inducing, single-stranded segment of DNA from the soil bacterium Agrobacterium tumefaciens integrates itself into the genome of plants after the bacterium infects plant wound sites.

The genes in this DNA segment trigger the synthesis of plant growth hormones and subsequent tumorous proliferation of plant cells, resulting in the agriculturally significant blight known as crown gall disease. While certain aspects of the DNA-transfer process are well understood, the mechanism that drives the DNA segment across the plasma membrane of the plant has remained a...

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