Published in Cancer Weekly, February 13th, 2001
The enzymes, called cathepsin D and procathepsin D, were identified in liquid growth media in which human prostate cancer cells had grown in the presence of plasminogen. Plasminogen is the parent compound of plasmin, a blood component that facilitates the disruption of blood clots.
Researchers say these compounds, via enzymatic reactions, work to generate angiostatic peptides from plasminogen. According to the investigators, angiostatin is an important...
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