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Apoptosis

Scientists Detail Key Molecular Pathway and Potential Drug Targets Against Cancer, Neurodegenerative Disease

Published in Cancer Weekly, March 20th, 2001

Molecular geneticists at the Kimmel Cancer Center of Jefferson Medical College are uncovering clues to how and why cancer cells grow with abandon, while at the same time, understanding why brain cells die too young in neurodegenerative illnesses such as Alzheimer's and Parkinson's diseases.

Understanding the molecular secrets of apoptosis, or programmed cell suicide, they say, will enable scientists to identify potential drug targets against these diseases.

Reporting the results of a study March 1, 2001, in the journal Nature, Emad Alnemri, PhD, professor of microbiology and immunology at Jefferson Medical College of Thomas Jefferson...

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