Nasopharyngeal Cancer
Researchers Clarify Associated Genetic Alterations
Published in Cancer Weekly, April 3rd, 2001
by N.R. Saltmarsh, staff medical writer - Researchers working at the U.S. National Institutes of Health have identified several chromosomal abnormalities in patients with nasopharyngeal cancer (NPC). Chromosomal gains involved chromosome arms 12q (24 cases, 51%), 4q (17 cases, 36%), 3q (16 cases, 34%), 1q (15 cases, 32%), and 18q (15 cases, 32%). Common regions of gain were 12q13-q15, 4q12-q21, and 3q21-q26. Chromosomal losses involved chromosome arms 16q (26 cases,...
Y. Fang and colleagues used comparative genomic hybridization (CGH) to analyze 57 NPC tumors, of which 47 displayed genetic alterations.
Among their results:
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Source: Cancer Weekly (2001-04-03)
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