Cancer Gene Therapy
Scientists Investigate How 'Knots' In DNA Affect Genes
Published in Cancer Weekly, April 10th, 2001
These knots occur when DNA folds over upon itself, creating a variety of complex, three-dimensional structures called quadruplexes. Some of these structures have been linked to known cancer genes and cancer-triggering processes and may harbor active sites that could be the targets for new drugs.
An update on research in this area was presented March 26, 2001, at the 92nd Annual Meeting of the American Association for Cancer Research. The presentation, "Secondary DNA structures as molecular targets for cancer...
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Source: Cancer Weekly (2001-04-10)
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