Published in Cancer Weekly, May 8th, 2001
While differentiation-inducing agents such as these have demonstrated minimal cancer inhibition when used as monotherapies in clinical experiments, a combination of these agents has resulted in marked effects in cultured cancer cells and in engrafted animals, Johns Hopkins researchers state.
"Our study evaluated the combination of phenylbutyrate (PE) and 13-cis retinoic acid (CRA) as a differentiation and anti-angiogenesis strategy for prostate cancer," R. Pili et al. said in...
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Source: Cancer Weekly (2001-05-08)
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