Published in Cancer Weekly, May 8th, 2001
Although a membrane-bound form of AAP is expressed by many cell types, J.Y. Meng and colleagues previously reported that a soluble form of the protein is secreted by human colon carcinoma cells. The secreted form inhibited serine proteinase most likely via a Kunitz-type inhibitor domain, they suggested.
In their current study, Meng et al. created a vector...
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