Published in Cancer Weekly, May 15th, 2001
To improve regional organ delivery of therapeutic genes, A.D. Brooks and colleagues perfused herpes simplex virus carrying a beta-galactosidase gene (HSVlac) into the lungs, livers, and bladders of rats. Brooks and coworkers reported in Surgery that following a 20-minute perfusion, HSVlac was expressed specifically in the treated organs. No tissue damage...
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