Fatigue

Paxil Is Effective Against Depression But Not Cancer-Related Fatigue

Published in Cancer Weekly, June 5th, 2001

A commonly-used antidepressant significantly relieves depression in cancer patients undergoing chemotherapy, but has less effect on fatigue, according to a study sponsored by the U.S. National Cancer Institute and conducted by community physicians.

The results suggest that fatigue in these patients may be more related to a patient's cancer and treatment, rather than depression.

Previous studies in the general population and several surveys of cancer patients have associated depression with increased fatigue, and animal models of low serotonin levels have also demonstrated a common link. Depression is associated with a decreased amount of serotonin...

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Source: Cancer Weekly (2001-06-05)

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