Gliomas

Genetically Engineered Poliovirus Fights Brain Tumors

Published in Cancer Weekly, June 5th, 2001

What do you get when you cross a poliovirus with the virus that causes the common cold'

An efficient mechanism for killing brain tumors, say scientists at Duke University, who have successfully used the genetically modified poliovirus to cure brain tumors in mice.

They reported their results at the 101st General Meeting of the American Society for Microbiology, held May 20-24, 2001, in Orlando, Florida.

"Malignant glioma (the most common type of brain tumor) is almost always fatal, due to very poor response to surgery, radiation, and chemotherapy," says Matthias Gromeier, in whose laboratory the research was conducted. "We...

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Source: Cancer Weekly (2001-06-05)

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