Published in Cancer Weekly, June 12th, 2001
The Tet System (TS) is a classic one used for tight regulation of gene expression in mammalian cells. In this system, transgene expression is regulated by the human cytomegalovirus immediate-early 1 gene promoter (HCMV1E) with tetracycline-repressible transactivator (tTA) operator sequences. This promoter is activated by tTA, which is a hybrid between the tetracycline repressor and the HSV transcriptional activator...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly