Acute Myeloid Leukemia

High-Dose Chemotherapy Improves Survival

Published in Cancer Weekly, June 12th, 2001

A short additional course of high-dose chemotherapy in the treatment of acute myeloid leukemia (AML) in children most at risk of relapse significantly improved their survival in a recent study.

The clinical outcome in two consecutive studies of two groups of children with AML was compared by researchers at the Children's Hospital in Munster, Germany. In one study conducted from 1987 to 1992, 307 patients were treated with standard dose chemotherapy during induction and consolidation chemotherapy, and in another study conducted from 1993 to 1998, two-thirds (310 patients who were at high risk of relapse) of 471 patients, received an additional short course of a...

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Source: Cancer Weekly (2001-06-12)

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