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Imaging Technology

Multiphoton Laser Scanning Microscopy Offers Look Inside Cancerous Tumors

Published in Cancer Weekly, July 31st, 2001

A powerful new with high resolution, three-dimensional imaging tool is providing researchers with never-before-seen views of what goes on deep within a living tumor.

Scientists at Massachusetts General Hospital (MGH) are using multiphoton laser scanning microscopy to visualize individual cells, where they can monitor gene expression, therapy effectiveness, and tumor cells' interactions with normal cells. A paper on the technology, published in the June 29, 2001, issue of Nature Medicine, indicates that the technique could be adapted to measure a wide range of physiological parameters.

Since the researchers use a living mouse model, they can...

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