Glioblastoma Multiforme

Possible Mechanism Of Brain Tumor Progression Identified

Published in Cancer Weekly, August 14th, 2001

Using a technique called gene array that permits analysis of thousands of genes in one experiment, scientists at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have identified a new mechanism that may be a critical step in the development of a type of malignant brain tumor that has historically been virtually impervious to treatment.

As a result of this study, scientists are gaining a better understanding of the way these highly malignant tumors (glioblastoma multiforme or GBM) impact and spread to surrounding tissues, how they develop a network of blood vessels that feed their growth (angiogenesis), and how lower-grade tumors become transformed into high-grade...

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Source: Cancer Weekly (2001-08-14)

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