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Oncolytic Viruses

Crippled Herpesvirus Is Transformed Into A Better Cancer Killer

Published in Cancer Weekly, August 14th, 2001

Scientists have found a way to greatly rev up the cancer-killing ability of a genetically engineered virus, a finding that may eventually lead to more potent anti-cancer therapies that capitalize on the ability of viruses to reproduce in the body.

New York University School of Medicine researchers report in a new study that they have isolated a new version of a herpesvirus that kills cancer cells but spares normal tissue. In animal studies, the new version dramatically reduced the size of human prostate cancer tumors grown in mice. Moreover, it completely eradicated the tumor mass in some of the animals, and it appears not to harm normal tissue.

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