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Leukemia

FIS-HAM Salvage Therapy Effective Despite Toxicity

Published in Cancer Weekly, August 21st, 2001

by Michael Greer, senior medical writer - A chemotherapy salvage regimen consisting of fludarabine, cytosine arabinoside, and mitoxantrone (FIS-HAM) is an effective treatment for advanced leukemia, despite its high toxicity, researchers in Germany report.

"Patients with refractory acute leukemias after intensive induction and salvage attempts have a particularly poor prognosis and therapeutic options are limited," according to Wolfgang Kern and colleagues at the University of Munich, Carl Gustav Carus University in Dresden, Georg August University in Gottingen, Westfalische Wilhelms University in Munster, and Braunschweig's City Hospital.

The FIS-HAM...

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