Hematological Cancer

IL-11 Allows Effective Pediatric Stem Cell Mobilization After Chemotherapy

Published in Cancer Weekly, September 11th, 2001

by Michael Greer, senior medical writer - Researchers in the United States say that the ICE chemotherapy regimen followed by interleukin (IL)-11 treatment enables clinically useful stem cell harvests from young relapsed cancer patients.

"Pediatric patients with solid tumors treated with prolonged dose-intensive chemoradiotherapy are poor mobilizers of peripheral blood stem cells (PBSC)," explained Dr. Mitchell S. Cairo at Columbia University and colleagues at the North Texas Hospital for Children (Dallas), Georgetown University's Lombardi Cancer Center (Washington, D.C.), the Children's Hospital of Orange County, California, and the National Institutes of Health in...

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Source: Cancer Weekly (2001-09-11)

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