Acute Myeloblastic Leukemia
Mitochondrial Depolarization Sensitivity Affects Drug Susceptibility
Published in Cancer Weekly, September 11th, 2001
"Nonresponse to remission-induction chemotherapy, which remains a major problem in [AML], has been linked to cellular resistance to apoptosis," explained Monica Pallis and colleagues at the University of Nottingham and Nottingham City Hospital in the U.K. and the Tyrolean Cancer Research Institute and the Institute of General and Experimental Pathology in Innsbruck, Austria. "Because the apoptosis induced by chemotherapeutic drugs is mediated by loss of...
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Source: Cancer Weekly (2001-09-11)
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