Adverse Effects

Ischemic Colitis Identified In Patient Taking Paclitaxel

Published in Cancer Weekly, September 25th, 2001

by Sonia Nichols, senior medical writer - Physicians in Italy have identified a rare case of ischemic colitis in a female patient taking paclitaxel for metastatic liver cancer.

According to doctors, pseudomembranous colitis is a more frequent side effect in patients who take cancer therapies than ischemic colitis, but in Naples, Italy, investigators at the National Cancer Institute reported that a patient on combination paclitaxel/carboplatin therapy was diagnosed with the rarer type of colitis.

"The patient developed symptoms of gastrointestinal toxicity with abdominal pain and bloody diarrhea, which resolved in about 10 days," described B. Daniele,...

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Source: Cancer Weekly (2001-09-25)

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