Functional Genomics

Duke Researchers Identify 10 Genes Believed To Protect Cancer Cells

Published in Cancer Weekly, September 25th, 2001

Cancer researchers at Duke University Medical Center have identified 10 genes believed to have significant roles in allowing cancerous tumors to thrive under oxygen-deficient conditions.

The discovery is the first step in what could eventually lead to new treatments for some of the deadliest forms of cancer. Led by Dr. Gregory J. Riggins, an assistant professor of pathology and genetics at Duke, the team sifted through 24,504 genes expressed in the oxygen-deprived (hypoxic) cells in glioblastoma multiforme, which is a form of brain cancer.

The researchers identified 10 genes, some of which can lead to the creation of new blood vessels that will...

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Source: Cancer Weekly (2001-09-25)

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