Published in Cancer Weekly, October 16th, 2001
Changes in the type of cell lining the lung from that of a simple one-cell layer to a multiple skin-like cell layer is a precancerous "metaplasia" event. Three of five ferrets exposed to tobacco smoke alone for six weeks developed metaplasia and it was no different (three out of five animals) when vitamin C and E and a high dose of beta-carotene was added to the diet. However, only one of six animals developed metaplasia if only vitamins C and E were fed; and none of...
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