Cancer Gene Therapy

'Double Suicide' Gene Therapy May Offer Safer Treatment For Prostrate Cancer

Published in Cancer Weekly, November 13th, 2001

A team of U.S. scientists has become one of the first in the world to use a novel form of double "suicide gene" therapy to treat prostate cancer - and it's done so with the help of a common cold virus.

The injected adenovirus is used as a vector (transporter) to carry pairs of fused suicide genes directly into the cancer cells. This is followed by administration of two so called "prodrugs," resulting in the secretion within the cancer cells of a toxic substance - which compels them to commit suicide.

The technique might sound simple, but exploiting the source of one of mankind's most common afflictions to attack one of its biggest killers highlights...

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Source: Cancer Weekly (2001-11-13)

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