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Pancreatic Cancer

Cell Receptor May Absorb Chemicals That Lead To Metastasis

Published in Cancer Weekly, February 5th, 2002

A specially designed cell receptor may reduce death rates from pancreatic and other cancers by sopping up excess tumor-produced chemicals like a sponge, a University of California-Irvine College of Medicine study has found.

The study, using human cancer cells in mice, helps explain the puzzling increases in certain chemicals seen in tumor cells and may help increase survival rates from pancreatic cancer, currently one of the world's deadliest.

Dr. Murray Korc, professor of medicine and chief of endocrinology at UCI Medical Center, and his colleagues found that the binding of growth factors to "dummy" receptors - ones incapable of sending signals to...

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