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Antitumorigenesis

Researchers Tailor Cancer Cells' Sugar Jackets To Inhibit Tumor Growth

Published in Cancer Weekly, February 12th, 2002

Massachusetts Institute of Technology (MIT) scientists wielding molecular scissors have shown for the first time that the sugar jackets of cancer cells can be tailored to inhibit tumors.

The work, which could lead to drugs that attack cancer cells in a very specific manner, was reported in the January 22, 2002, issue of the Proceedings of the National Academy of Sciences USA.

The web of material that surrounds every cell, known as the extracellular matrix, is critical to cell function, orchestrating how signals from outside the cell are processed and perceived by it. The key components of that web are complex sugars and proteins.

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