Published in Cancer Weekly, March 19th, 2002
"Chronic lymphocytic leukemia (CLL) cells are long lived in vivo but undergo spontaneous apoptosis when cultured in vitro," explained Dr. Elizabeth C. Moran and colleagues at the Royal Liverpool University Hospital in Liverpool. "Intriguingly, CLL cells also appear to have a specific susceptibility to oxidative stress - a potent inducer of apoptosis."
Moran and coauthors identified a number of factors that protect CLL cells from oxidative stress in circulation and in tissues.
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