Acute Myeloid Leukemia

Autologous bone marrow cells appropriate for directed gene therapies

Published in Cancer Weekly, March 19th, 2002

by Sonia Nichols, senior medical writer - Bone marrow cells isolated from patients with acute myelogenous (myeloid) leukemia may prove to play significant roles in directed gene therapies.

More specifically, autologous bone marrow stromal fibroblasts (BMSF) obtained from those with acute myeloid leukemia have demonstrated they can be transduced with retroviral and adenoviral vectors encoding for different types of genes with significant transduction efficiency.

Working at Yonsei University College of Medicine in Seoul, South Korea, Y.H. Min and the coauthors of a recent study recently described how they isolated and checked the cells for transduction...

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Source: Cancer Weekly (2002-03-19)

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