Cancer Therapy

Acute myeloid leukemia model may be important research tool for many cancer treatments

Published in Cancer Weekly, April 2nd, 2002

A method that enables scientists to study the development of an acute myeloid leukemia (AML) in mice should open new research paths for scientists studying cancer in humans.

The findings were published in the February 26, 2002, edition of the journal Cancer Cell by scientists at St. Jude Children's Research Hospital. James R. Downing, MD, chairman of the St. Jude Pathology department, led the research.

The study is the first to give scientists a way to control the genetic expression of specific cellular targets. The method, known as modeling, involved implanting into mice a mutated protein considered a trigger of AML. Though modeling is...

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Source: Cancer Weekly (2002-04-02)

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