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Gastroenterology

Researchers find protein signpost may indicate esophageal and stomach cancer

Published in Cancer Weekly, April 23rd, 2002

A protein marker whose presence is thought to indicate the return of colorectal cancer may also be a sign of the development of esophageal and stomach cancer.

Researchers at Jefferson Medical College have shown for the first time that the protein, GCC, is present in a condition known as intestinal metaplasia, which may lead to both cancers, and in turn, is also present in those cancers.

The work, led by Stephanie Shulz, PhD, assistant professor of medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia, and Jason Park, an MD/PhD student at Jefferson Medical College, has implications for the development of improved methods...

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