Tumor Suppression
Novel agent SI-27 halts angiogenesis in laboratory studies
Published in Cancer Weekly, May 14th, 2002
SI-27 has been tested on human endothelial cells at Tokyo, Japan's Nippon Medical School. Those test results show SI-27 prevents angiogenesis by blocking matrix metalloproteinases (MMPs), or enzymes that degrade extracellular proteins. Because of this specificity, SI-27 holds the potential for being a useful therapy for selected diseases caused by pathologic angiogenesis.
Daizo Yoshida and associates in the Department of Neurosurgery coauthored the study with colleagues in the Central Institute for Electron...
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Source: Cancer Weekly (2002-05-14)
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