Leukemia

Arsenic trioxide may be effective against resistant forms

Published in Cancer Weekly, May 28th, 2002

by Michael Greer, senior medical writer - The antineoplastic agent arsenic trioxide (ATO) shows promise for the treatment of some drug-resistant forms of leukemia, researchers in France report.

"T-cell prolymphocytic leukemia (T-PLL) is a rare form of mature T-cell leukemia that is generally resistant to conventional chemotherapy," explained Dr. Christian Recher and colleagues at Saint Louis Hospital and Fernand Widal Hospital in Paris.

Animals suffering from this form of malignancy showed positive responses to ATO treatment, the researchers found.

Recher and coauthors studied mice engineered to carry the oncogene MTCP1,...

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Source: Cancer Weekly (2002-05-28)

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