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Renal Cell Cancer

Phase I/II clinical trial of CpG 7909 initiated

Published in Cancer Weekly, June 4th, 2002

Coley Pharmaceutical Group, Inc., announced that it has initiated a multicenter open label, phase I/II clinical trial of its lead product candidate, CpG 7909, for the treatment of patients with stage IV (metastatic) renal cell carcinoma.

The phase I study will assess the safety and tolerability of escalating doses of CpG 7909. Once these are established, a phase II group of patients will be enrolled to determine overall tumor response and immunologic effects. Other endpoints of the phase II portion of the study include time to disease progression, duration of response and survival time.

"Because our CpG 7909 product candidate stimulates multiple...

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