Acute Myeloid Leukemia

Microenvironment rules angiogenesis in hematological cancer

Published in Cancer Weekly, June 4th, 2002

by Sonia Nichols, senior medical writer - A new report lends additional support to increasing evidence of angiogenic mechanisms in acute myeloid leukemia (AML) although previous studies diverge on where those mechanisms stem from. In the latest of reports, researchers in Canada say AML angiogenesis is microenvironment dependent.

Craig Litwin and colleagues, University of British Columbia, Vancouver, Canada, described in American Journal of Hematology why they believe the microenvironment, rather than intrinsic cellular control, modulates bone marrow angiogenesis in patients with AML, based on the many assays they have performed.

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Source: Cancer Weekly (2002-06-04)

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