Published in Cancer Weekly, June 18th, 2002
Scientists report connective tissue growth factor (CTGF) is just one of several known modulators of angiogenesis, or neovascularization. S. Kondo and colleagues at Okayama University Graduate School of Medicine and Dentistry of Okayama, Japan recently reported that hypoxia-induced CTGF can lead to a cascade of events culminating in vascular invasion.
In the researchers' study, they used human breast cancer cells (MDA231) and...
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