Metastasis

Gene for syntenin is overexpressed in metastatic breast and gastric cancers

Published in Cancer Weekly, July 2nd, 2002

by Sonia Nichols, senior medical writer - Medical researchers in Korea have identified the gene for a protein that appears to correlate with the spread of some cancers.

The gene for syntenin is overexpressed in certain invasive breast cancer cell lines and upom forced expression in gastric cancer cells, correlates with migration and invasion, scientists report. Therapeutic strategies targeting the syntenin gene might be of benefit for reducing cancer cell dissemination in some individuals.

The syntenin gene stood out as a metastasis candidate when researchers at the Korea Research Institute of Bioscience and Biotechnology identified 17 cDNAs that...

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Source: Cancer Weekly (2002-07-02)

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