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Breast Cancer

Research into rare disease leads to discovery of six new breast cancer-susceptibility genes

Published in Cancer Weekly, July 9th, 2002

A decade of research into one of the world's least-known diseases has resulted in a major advance against one of the best-known: the discovery of six genes linked to inherited breast cancer.

In a study published online by the journal Science (www.sciencemag.org) on June 13, 2002, investigators at Dana-Farber Cancer Institute and Children's Hospital Boston report that an error in any of the half-dozen genes involved in Fanconi anemia - a rare childhood condition - can increase an individual's chances of developing breast cancer. The discovery raises the prospect that the ranks of known breast cancer-susceptibility genes - best known as BRCA1 and BRCA2 - will soon...

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