Published in Cancer Weekly, July 30th, 2002
BRCA1 and BRCA2 are tumor suppressor genes that play important roles in cellular functioning such as DNA damage repair. Mutations in these genes have been associated with 5-10% of epithelial ovarian cancers. Whether BRCA1 and BRCA2 mutations lead to cancer through similar or different pathways is unclear. A past study of BRCA1 and BRCA2-linked breast cancers...
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