Cervical Cancer

Tissue changes may explain false-negative Pap smears

Published in Cancer Weekly, July 30th, 2002

Some women may be getting false-negative results on their routine Pap tests because aberrant tissue changes can keep abnormal cells from being picked up during the exam, according to a new study.

Writing in the June 2002 issue of the American Journal of Obstetrics & Gynecology, physicians at the Keck School of Medicine, University of Southern California (USC) and colleagues in California and Taiwan are the first to suggest this explanation for the frequent occurrence of false-negative Pap smears.

Nationwide, physicians perform about 55 million Pap tests every year to look for cervical cells that are becoming abnormal, a precursor to cancer. ...

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Source: Cancer Weekly (2002-07-30)

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