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Hepatocellular Carcinoma

Viral infection supercedes familial genetics in risk for primary liver cancer

Published in Cancer Weekly, July 30th, 2002

by Sonia Nichols, senior medical writer - The results of a long-term study have placed infectivity over heredity in familial tendencies for developing hepatocellular carcinoma (HCC).

Hepatitis C virus (HCV) and hepatitis B virus (HBV) infections are two of the most common causes of hepatocellular carcinoma, a primary form of liver cancer. After studying more than 15,000 relatives of HCC patients, medical investigators in Japan say viral infection, rather than genetics, is a reason for HCC prevalence within some families.

For 5 years, Dar-In Tai and colleagues, Chang Gung Memorial Hospital, Taipei, Taiwan, screened the relatives of HCC patients for...

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