Multiple Myeloma

New test identifies B-cell tumor markers

Published in Cancer Weekly, August 27th, 2002

In the United States, multiple myeloma accounts for about 1% of all cancers, and approximately 12,500 new cases are diagnosed every year. This uncommon cancer affects men and women equally, and is usually seen in people over 40 years old. Its cause is unknown.

Current methods for identifying and monitoring patients' B-cell lineage tumors such as myeloma rely on electrophoresis-based testing for Bence-Jones (BJ) proteins, which are homogeneous populations of k or l free light chain (FLC) molecules produced by malignant B-cell clones. This type of testing, usually performed on urine specimens, is expensive, time-consuming and sometimes inaccurate.

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Source: Cancer Weekly (2002-08-27)

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