Published in Cancer Weekly, October 15th, 2002
"Although the mechanism is unknown, infiltration anesthetics are believed to have membrane-stabilizing action," wrote T. Mammoto and colleagues, Osaka Medical Center for Cancer and Cardiovascular Disease.
"We report here that such a most commonly used anesthetic, lidocaine, effectively inhibited the invasive ability of human cancer (HT1080, HOS, and RPMI-7951) cells at concentrations used in surgical operations (5-20 mM)."
According to Mammoto and coauthors, "Ectodomain shedding of heparin-binding...
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