Thyroid Follicular Neoplasms

Study compares proliferation markers as diagnostic adjuncts

Published in Cancer Weekly, October 22nd, 2002

Researchers in India conducted a study "to differentiate hyperplastic nodules (HPN), follicular adenoma (FA) and follicular carcinoma (FCA) of the thyroid by cytomorphologic features combined with argyrophilic nucleolar organizer regions (AgNORs) and Ki-67 proliferative markers on fine needle aspiration cytology."

"Cytomorphologic patterns, along with two proliferation markers, Ki-67 and AgNORs, in fine needle aspirates of 123 histologically confirmed cases of thyroid follicular lesions, including 39 hyperplastic nodules, 70 follicular adenomas and 14 cases of follicular carcinomas, were recorded," wrote A. Mehrotra and colleagues, King George's Medical College,...

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Source: Cancer Weekly (2002-10-22)

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