Liver Metastasis

Combining chemotherapy with vessel inhibitors multiplies antitumor effects

Published in Cancer Weekly, October 22nd, 2002

by Sonia Nichols, senior medical writer - Cancer treatment regimens combining chemotherapy and natural angiogenesis inhibitors such as endostatin and angiostatin can improve outcomes in models of early metastatic colorectal cancer.

Individuals with colorectal cancer often face the risk of their cancer cells migrating to the liver. Researchers in the Netherlands have advised that combining standard chemotherapy with proteins that prevent tumor neovascularization can reduce tumor involvement and increase survival in murine models of early colorectal liver metastasis.

In the animal model study, E.A. te Velde and colleagues, University Medical Center...

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Source: Cancer Weekly (2002-10-22)

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