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Head and Neck Cancer

High-risk tumors largely resist chemotherapy attack

Published in Cancer Weekly, November 5th, 2002

Adding chemotherapy to radiation therapy and surgery failed to significantly improve control of high-risk, resected head and neck cancers, according to a new study presented at the October 2002 American Society for Therapeutic Radiology and Oncology's Annual Meeting in New Orleans.

Researchers set out to discover whether the most aggressive, high-risk squamous cell carcinoma patients who had their cancers surgically removed were less likely to have local or regional recurrence of the disease if the chemotherapy drug cisplatin was given concurrently with postoperative radiation therapy.

A total of 459 patients were enrolled in the study. Patients...

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