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Head and Neck Cancer

P53 suppressor gene studied

Published in Cancer Weekly, November 5th, 2002

Montefiore Medical Center researchers are studying a new drug that has the potential to fight recurrent and highly resistant head and neck cancer. Montefiore is the only medical center in New York City involved in the phase III, multi-institutional national study that will enroll 140 people.

"The drug is designed to kill the cancer cells and to stop tumor growth by using what is called the p53 suppressor gene," said Missak Haigentz, MD, an oncologist and principal investigator for the study at Montefiore. The p53 gene, when mutated, is frequently associated with the unregulated growth of cancer cells.

Head and neck cancers account for approximately...

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