Cell Biology

Researchers identify a new gene essential for the natural killer cell response against cancer

Published in Cancer Weekly, November 19th, 2002

Two parts of the body's immune system are critical for its normal functioning. One of these, the innate immune component, must defend the body against onslaughts from foreign substances it has never before seen.

Failure of the immune system can result in cancer, autoimmune disease, or life-threatening viral infections. Scientists at Memorial Sloan-Kettering Cancer Center have identified a gene called MEF that is essential to the development of natural killer cells and natural killer T-cells, which play a vital role in the innate immune system. Their findings were published in the journal Immunity (2002;17(4):437).

"By understanding how the...

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Source: Cancer Weekly (2002-11-19)

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