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Lymphoma

Discovery may lead researchers to genetic mutations causing the cancer

Published in Cancer Weekly, November 26th, 2002

Scientists at UCLA's Jonsson Cancer Center have developed the world's first animal model for mature human B-cell lymphomas, a discovery that may lead to the uncovering of the genetic mutations that cause these types of cancer. About 85% of all lymphomas are mature B-cell type.

The basic science discovery is outlined in the October 29, 2002, issue of the peer-reviewed journal Proceedings of the National Academy of Sciences USA.

"What we can do now is grow cell lines out of this model to determine which cancer-causing companion mutations arise," said Dr. Mike Teitell, a physician and researcher at UCLA's Jonsson Cancer Center and the lead...

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